I often ask myself if the nature of the disease itself make it even worse: AIDS was the worst in its age, people went in streets asking for a cure, now we made huge steps, the same it's happening with cancer, but Alz make everything different: the sick can't make his voice heard, he has no knowledge of what's happening, family, with an enormous economic sacrifice, try to take care of the sick, and their voices become silent.
I'm seeing this for the second time in my family and I can say that I can fully understand who rely in special clinics - Switzerland is famous for this - to stop their life once the disease make them not self-sufficient. A nice view of this situation is given by "Terry Pratchett: Choosing to Die".