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Well, just don't get lost. I've taken LSD hundreds of times and the worst was undoubtedly in nature (it was my fault, but I'm sure I'm not the first to make this mistake). I've done it plenty of times at house parties and it's been fine. My objection to a "clinical setting" is being alone with someone you don't know that well, and like you said, being confined and expected / forced to stay with that person.

> A clinic, concert, or house party are all terrible settings for taking LSD.

That's certainly the main reason for "bad trips". People just don't bother to read up on everything properly before the trip. So they do stupid things. And then it's the substance's fault.

My definition of clinical setting certainly includes nature, though I don't think that's required. The important part is professionals that first screen people (weed out people deemed to be high risk for bad episodes) and guides the process. A captain to steer the boat if you will.