I think the method (MLM as opposed to a person who is just selling something) is immoral in the same vein that gambling is.
Because it's a consuming and addictive negative expectations game that (generally) takes a persons money and effort without growing the social pie so to speak.
It feeds on persons natural desire to better themselves, to make it in life but this effort is subverted into the pockets of hucksters and scammers rather than actually producing good for the world. In this sense it's like pornography as it subverts a natural tendency into nonproductive or counterproductive outlets.
People become wrapped up in these schemes, they ruin relationships, families and lives. I find this very immoral.