That's super interesting. Would you be willing to share some of your background on this? I'm quite curious about this route.
There are tons of how-tos on line. Keywords are "CRADA", "technology transfer" (T2) and pick a noun or verb of your choice. Every federal department and agency has some sort of "T2" program with people who will even help write the CRADA for you. Commerce, Interior, HHS, all of them.
The key items are to write an effective statement of work and a budget. And understand these things are designed to accomodate big, enormous projects. Act of Congress scale projects. So, if you're going to think, you might as well think big. The paperwork is the same, big or small.