Also, it’s a clinical study. They need to control the conditions or it’s not science.
Just adjacent to her office was a "trip room", probably constructed when the building was build in the 70s (?). It was round, completely lined with acid orange fabric, upholstered like a pasha's tent and filled with cushions in every colour imaginable. No doubt it had a superlative quadraphonic sound system installed. It also had a large, smoked glass window, for "observers." Not ideal for mushrooms perhaps but for other things...
The conditions are almost a sure fire way to make someone have a troubling experience if they were given the doses knowen to be taken in those times and did not have prior experience dealing with the reality altering effects of those substances.