Every time the jury is out on a topic where one side has a vested interest and a billion dollar budget to protect it, you can be reasonably sure what the outcome will be. See: pesticides and bees, fossil fuels and climate change, food packaging plastics and cancer, pain treatment meds and addiction. The answer in all those cases is the harmful effects eventually became known, but the jury was out long enough for the vested interests to make a ton of profit and cause a ton of damage which they'll never pay for repairing. All made possible with a series of comparatively small investments to buy scientific research to keep the jury out.
Even in non-borderline cases like tobacco, lots of money and power can really confuse the issue. This is definitely not as clear cut as tobacco, and I’d like the option to opt out of the lengthy, massive “trial period” in which the public gets to play guinea pig. The problem with this is that it’s very difficult to do that when the compound in question is unexpectedly ubiquitous.