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Not a chemist but according to the providers I’ve talked to the recreational dose is an order of magnitude larger than that given for depression. My understanding is the dose for depression is relatively small (even compared to what’s used during, say, anaesthesia).

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Not an order of magnitude. Maybe 1.5-2x. Antidepressant doses are not far off of recreational for most recreational users.

The recreational doses are also relatively small (10-50%) compared to anesthetic doses, too. Being unconscious isn’t the recreational user’s aim.

I've had K for anesthesia at the oral surgeon's, and it did not make me unconscious. It put me in a K hole. I was conscious the way you're conscious in a narrative dream. I have pretty clear memories of the experience (trip) - just no memory of my teeth being extracted.

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