Check 'I am an advanced user' in the settings, then click on either 'requests blocked' or 'domains connected' in the drop-down to access dynamic filtering. Block everything third-party by default by clicking in the right side of the second column. Load a site with lots of third-party content, disable the block (by clicking in the middle of the third column, greying-out the block) for only those things which seem to be essential to show page content and you're done.

While not as fine-grained as uMatrix, uBlock Origin generally is the quicker way to go from 'empty page' to 'only the content I want' on sites which, without blocking, are tracker-ridden dark-pattern hell-holes.