I'd say science makes the future more uncertain, not less, by giving us more tools to change it. It's easier to figure out how to change things than to understand the impact of those changes.
Not sure if that's too abstract, but your statement that "the world has been significantly less predictable since the Enlightenment" made me wonder, because you'd think "less predictable" means that understanding has gone down.
Of course our understanding has increased. But that has generated rapid and accelerating changes in society and a monumental increase in its complexity, which together, make it significantly harder to predict the future of the social world.
I am not saying that we don't have a better predictive grasp of the natural world. We obviously do.