You should treat the lead debris you generate as any other poison. (how have you been treating it?)
As far as soldering safely, you should definitely keep in mind that your biggest health risk is inhaling burnt flux, and lead-free solder generates a lot more of that smoke. Lead-free solder is more dangerous to your health. There's some more information here (archive.org because I don't know where this is on the new Weller site): https://web.archive.org/web/20160402062321/http://www.weller...