The reason the US is a single country is because the Union fought a war to bring the South back into line. It has already split, and it could split again.
California could quit if a dictator arises, a threat that was unthinkable a decade ago but is now unnervingly probable. Other states like Vermont would likely cut loose as well, they don't have time for that.
> During the Civil War there was still a strong notion of states' rights, today there is not and the country is a lot more similar than different.
I'd argue that people more strongly identify with their home state than with some vague concept of "America", especially when it comes to states like California, Texas and Florida that have their own identity. The more these states differentiate, the more likely they are to disagree, and from there, eventually split.
Europe's had a long time to end up in its current state, and it's still shifting wildly. Belgium might split in half. Spain might rip apart. England might lose Scotland. Ireland might get unified. Nothing stays static for long.
Consider the United States in its current form only really came about in 1912. That's basically yesterday in terms of history. To think that will remain static for another hundred years is ridiculous.