Have there been many wildly successful tech startups that were based on the premise "save money", to the point that they located themselves some place incredibly cheap (but far outside of tech industry circles)?
I'm not saying it isn't a valid business plan, as I don't know, but I can point to an awful lot of Silicon Valley startups that have been wildly successful, and no wildly successful tech startups from Idaho. It's really cheap to live in Idaho, so you've got a REALLY long runway. Why aren't there success stories? (Expand it to the whole midwest, and the story isn't remarkably better.)
Then again, Kevin Hale from Wufoo told me a great story about a technique he uses in one of his presentations (which are awesome)...he passes around printouts about the top 20 or so fastest growing companies according to Inc. Magazine, and asks questions about them, asking folks to raise their hand if the answer is "yes". One of the questions is "Is the company you're looking at based in California or Boston or New York?" and only one or two hands go up (Wufoo is based in Florida, and thus they take great satisfaction in talking about successful companies outside of the tech startup hubs). But, Inc. Magazine covers stuff that isn't tech.