End user expectations are for complex layouts, flexible typography, rich media embedding, animated interactions, and so on. I've yet to see a QT app come close to what e.g. Slack has managed to shoehorn in.
It'd be great if we could get desktop level robustness out of it too, instead of being limited to scrolling three or four screens up before it has to start paging out content.
Web UI is bad in many ways, but many desktop adherents seem willfully oblivious about why there is such a desire for this. The only native OS that has evolved to compete is MacOS, with its multi touch driven interactions genuinely making most web stuff feel like the janky lowest common denominator that it is.