Sure, the question is how experimental of a plan can you attempt. In SF 2018: not very. I know people who pooled their money for an experimental space in SF several years ago at $1/sq. foot, and broke even. At 5x or 10x those rates today, this is now a lot harder.
> SV has it's issues for sure, but I wouldn't throw all cities under the bus with it.
My critique is specifically of the negative effects of overcrowding and overcapitalization in the SF Bay Area. By extension this would presumably apply to other places like Manhattan with similar conditions. I'm definitely interested in finding other cities with the networking advantages but that manage to strike a balance with livability. Austin has been mentioned already, although some folks will complain they're headed in the same direction.