On Prince Edward Island (PEI) phrases like 'Up West' and 'Down East' are the norm which seems pretty weird at first. But once you look at the orientation of the island on a map [1] it starts to make some sense.

Basically people think of the island as being laid out East to West but in reality the island is rotated ~45 degrees on the actual map. So West is really North-West and East is South-East. This leads to people combining the usual North = Up and South = Down with East-West qualifiers.

[1] https://www.google.ca/maps/place/Prince+Edward+Island/@46.64...