I remember a few bumps around 08..2010 where I ran beta builds because of some bugs. Also, I used to have extensions that colorized patches and highlighted quotes/threads... but those eventually broke and disappeared.
So, right now I am running a stock Thunderbird with a few profile customizations that tweak fonts (colors and sizes). Hitting GMail (work) and Fastmail (home) servers every minute or so.
Go Thunderbird!
It would also be nice to have a proper three vertical pane view. The way it currently works is horrendous.
What's wrong with View > Layout > Vertical view? Not my preference, just curious what's different as superficially it looks like other such programs.
Everything else works as it should. I'm not using calendars or syncing address books which probably places me in the long tail of the user distribution.
and instead it provides an input box, one per line, per email address. When you have a large to list, this gets painful.