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I was thinking about Peter Duesberg. He has been really pushing the aneuploidy idea for a few decades now, but everyone ignores him since he is a "denier":

http://www.newsweek.com/can-hiv-denying-scientist-cure-cance...

It'd be pretty funny if he turned out to be correct.

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I don't really know any history about cancer research, but as long as I've been in genomics people have talked about it. Difficulty is actually finding CNVs. These days it's not so hard.

It's also important to remember that we know some cancers (leukemia for instance) are diploid and rarely develop anueploidy.

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