If you're using JIRA for stuff that Trello works for, then sure.
What JIRA does and does exceptionally well: grows with your organisation. You can start using JIRA for a simple ticketing system with 3 devs, then continue using it through 100x growth and still use it with multiple product teams, multiple development teams, overlapping projects, CI, code review, wikis, reporting tools, and so on.
If you think that all these tools and sophistication is bullshit, then that's a different conversation -- but a non-negligible number of smart people think that these integrations worth a lot.
JIRA is like Excel or Word -- 80% of people use only 20% of the functionality (or less), but it's a different 20% for all of them. And it's really-really painful to realize that Trello/GH Issues/etc. works great with a slick UI, except that it can't do that single stuff you'd really need because of your special situation.