Cleese talks about how multitasking is destructive to the creative process (at time code 6m:30s):

"But if you're racing around all day, ticking things off on lists, looking at your watch, making phone calls, and generally just keeping all the balls in the air, you are not going to have any creative ideas."

I find it hilariously ironic that immediately after he says this, the camera cuts over to two guys in the audience clicking away on their laptops while ostensibly listening to Cleese's talk.