Not even taking into account that a Germany resident could get public health care, lower cost for transportation, and could live and work in most areas without ever needing a car.
There is considerably less income inequality. Because your specific profession makes less isn't necessarily a bad thing.
Also, my point is exactly that many countries consider you "poor" if you have to work 70+ hours per week and get 2 weeks (or no) leave, even if you make $150k. That's why I said many OECD countries consider Americans "poor". (in quotes). Not poor in the sense of not much money, but "poor" in the broader sense.
But how much of that gap is left if you factor in things like health care, access to education and infrastructure?
Costs of living in Luxembourg are about the same as in Santa Barbara (where I currently live).
I think median salaries in Luxembourg might be skewed by the presence of a large financial market (it's kind of a Wall St of Europe).
The prevailing wage law of the H1B is only $60k, and these are for the best and brightest workers our mega corps need, due to a lack of qualified US workers.
So obviously, $50k is more than adequate. /s