EDIT: I was mobile earlier but wanted to throw a bit of a teaser in here. This book (along with Hager's "The Demon Under the Microscope) are excellent reads and I high recommend them.
Essentially, there were many "doomsday scenarios" wherein the context of the late 1800s was that vast supplies of natural fertilizer were used up and people were very worried about food supplies. Long story short, the "fixing" of nitrogen from the air not only alleviated the short term issues but also had a huge influence in wars and who was in power in the early 20th Century.
Consequently, this books ends with some pretty questions surrounding the impact of what all of this extraneous nitrogen might do long term—the impacts of which are already seen in rivers and streams... but the ocean and other areas as well.