I wonder if it would be very useful in a moon base to actually launch further into the universe considering the lower gravity well. With a single fusion power point and just using moon materials to make a single launch point outside of earth. You wouldn't need to 'colonize' the moon in that a single base could make more practical sense.

That being said, how much He-3 do we really need for fusion? I was under the impression fusion reactions lasted a very long time considering the energy output to mass used, so would mining the substance once or twice suffice for as many fusion reactors as we would need on Earth? Total energy usage across the globe was about 18.0 terawatts in 2013, and apparently the ITER fusion reactor would produce 500 Megawatts of power using a 1/2 gram of hydrogen per year [1], so if Helium 3 was more efficient, we would need hardly any to cover global power generation, and even plan for future power usage.

[1] https://www.extremetech.com/extreme/123837-500mw-from-half-a...