The only hardship you might experience from taking such a job is the ribbing you'd get from future potential employers, partners, investors and co-workers.
I personally used to work with a fellow years ago who worked for a server hardware vendor in the north east that had large companies(financial, aerospace) and government and military clients. He told me several stories where he went to non-descript massive underground data centers to do work that to this day he is not allowed to identify. On his resume, he too could only say the type of work he did and could not identify the clients due to NDA.