That's why I prefer to play games in fullscreen as opposed to "borderless windowed", I have noticed quite a bit of input lag in the latter mode.
https://msdn.microsoft.com/en-us/library/windows/desktop/dd3...
In my experience the vast majority of games that I play don't suffer any perceptible ill effect from running in borderless fullscreen. If you're playing the game competitively it's another story, but for me running around shooting aliens in Destiny 2 or something I haven't noticed any degradation of my experience. There's of course the odd (usually older) game that doesn't support borderless fullscreen, but sometimes there are mods to support it.