There are new challenges there but it's also very high-reward. You can sell 1000 licenses from a single deal with a school. If you get a government public school contract you could be looking at 100k licenses from a single deal.
I think that companies which do big b2b deals have become greatly undervalued. VCs are so obsessed chasing exponential growth curves that they seem to have forgotten that the earth only has limited population and that buying power has become much more centralized and is becoming increasingly centralized.