In principle, but...
Venture capitalists for example are notorious for investing in startups and replacing the founder and/or CEO with "more experienced management" as the company grows.
A well known prominent example is the ouster of Steve Jobs at Apple in the 1980s by John Sculley whom Jobs had supposedly hired -- with the support of the lead investors such as "Mike" Markkula and Arthur Rock.
Steve Jobs is not an unusual case. The founders of Cisco Sandy Lerner and Len Bosack were ousted by Don Valentine/Sequoia:
http://www.businessinsider.com/how-ciscos-founders-were-oust...
There are many other examples.