I have a macbook, mac mini, iPad and formerly used an iPhone. iTunes was the worst part of that.
I simply never plug any of that stuff into my computer unless I really need to get photos or something off of it. That's a usability pain. It doesn't help that I have more music than can fit on my computer, so I also have to hook up an external drive whenever I use iTunes.
Every one of my Apple devices has high speed internet service any time I'm using them.
I carry a Nexus One now. My calendars, contact lists, etc... are always up to date. Things Android doesn't ship with are alway up-to-date, such as my instapaper offline reading list, twitter, RSS feeds, SMS and voicemail from google voice and other junk.
And speaking of integration, the fact that my browser is notified of my SMS and I can respond from there is just awesome. And when I do respond from my browser, the message is marked as read on my phone. Apple is just way behind here.