Hi there! One of the Skulpt maintainers here. (Also founder of Anvil - https://anvil.works. Never thought I'd have two projects on the front page at once!)

Feel free to ask any questions about the gory internals and how it works. You might also enjoy my talk from PyCon US this summer, about how Skulpt compiles blocking Python code into non-blocking Javascript: https://anvil.works/blog/pycon-talk