I would expect anybody working with DAWs and sample libraries (extremely low latency random read performance needed, meaning every note playing can be a sample anywhere on your drive) would jump at these, both pros and amateurs.
I use Spitfire stuff, mainly Albion, but the voice requirements these guys have is on another level. The Optane speedup would certainly mean more voices, and perhaps remove the need to have separate SSD's for each large kontakt library?