Depends on case, for me NFS performance (MacOS as host, Linux as guest) is a major PITA and source of instability in vagrant dev setup.
e.g. tcp mounts, getting read/write blocks matched up btw/client server and sized to be digestable but big enough to move data, etc.
also, nfs is mainly only suited for 'NAS-like' operations - things like rdbms's do waay better on iscsi or eating the vdisk performance.
last I messed with macos nfsd (which has been a while), it a way happier with smaller blocksizes (e.g. 8-64k range) - modern linuces will attempt 1MB which is too much for the older 4.4BSD based code
another thing to look at is timeouts / backoffs - it's easy to kill performance by setting these things too agressively so that the system double-chokes when it gets bogged down..