Quoting the talk:
> But I do think that it would be kind of a shame if in forty years we’re still coding in procedures and text files in a sequential programing model. I think that would suggest we didn’t learn anything from this really fertile period in computer science. So that would kind of be a tragedy.
Lots of people seem aware of the idea of coding without text files. There are some "visual" programming environments with traction (in the game dev world, Max/MSP). I'm even working on one myself! But there are significant downsides/challenges associated with this approach (more difficult to version control, often tied to one editor, etc.). So to his quote, the fact that we're still coding in text files may not be because we didn't learn anything, but because the idea of non-textual programming is hard to form into a product that more people want to use.
I agree with you that his talk is very valuable in terms of drawing attention to ideas that deserve more exploration, and I love the talk. It's just this one facet that I take issue with, the suggestion that the ideas haven't caught on because nobody appreciates them. His talks are frequently at the top of HN, they are widely appreciated. People have been super excited about related projects, like Light Table and Eve, and yet they haven't gotten much traction. So I think it's worth acknowledging that the problem is less idea-awareness and more compelling-implementation-difficulty.