The mean distance between Earth and Mars is about 1338 light-seconds, or about 22 minutes. You wouldn't be able to have a meaningful phone call with your friends or relatives at Earth -- you'd be stuck with writing long e-mails or voice messages. That would suck.
Building a CDN between Earth and Mars would also be a technical nightmare. Especially for whatever data-hungry VR and other content we'll have at that time.
Everything else about making Mars habitable -- climate control, resources, food, water, medical, cultural, job opportunities, transportation, recreation, entertainment -- seems approachable to me in the next few thousand years of technological development.
The speed of light will suck. Unless Einstein is wrong in some way we don't yet understand.