Not necessarily to skill, but to exposure to programming in general.
I'd wager that people (kids) get interested in programming by using technology and wondering, "Hey, how does this work?" I'd further bet that this occurs far more often in connection to video games than, say, Word or Outlook, since video games are fun and creative. For the past few decades, far more boys than girls play video games. Hence, by college, more young men have been exposed to programming than young women.
Now, with the advent of the web (which is more or less gender neutral) and social gaming, I expect to see an increase in the number of women getting into programming over the next decade. Nowadays, it seems to me that there are more "fun" things that programming has made possible which have yet to be skewed towards the Y chromosome.