It worked for Gandhi fighting (or rather, not fighting) the British. Superior weaponry doesn't necessarily lead to victory in this kind of conflict.
We hope that there would be enough good people among the wealthy and powerful to avoid such a scenario--but would there? Do we know that for certain? I don't think we do. Look at how the wealthy and powerful already exploit people on both small and large scales, from Hollywood execs satisfying their sexual desires one victim at a time, to corporate execs exploiting cheap overseas labor that, to them, are merely numbers on a screen, helping them increase margins.
It all boils down to the same problem in the end, that of evil, and it's not going away, merely taking different forms throughout the ages.
What's changed since then is that an extreme minority can kill far more people. For instance, automated drones.