Except you're going about it the wrong way. We've eaten simple unrefined foods for as long as society has existed. For example, what only existed recently has been highly refined seed oils like corn, rapeseed, and canola.
It is up to them to prove that they are safe for human consumption, something that they have been unable to do. However, to continue the example, those types of oils are high in PUFAs (and specifically, high in Omega 6), and this has been linked to basically every modern first world disease, including diabetes and cancer.
The same applies to grains: cereals such as wheat hybridize in ways that are unusual. There is probably a level of certain chemicals (such as, but not limited to, prolamins, agglutinin, and amylase trypsin inhibitors) that are safe for human consumption, but the hybridization of these grasses for modern commercial production have greatly increased the amount of these chemicals in a given food product.
Just like the oils, these hybrids are a recent invention and no science was done before they were pushed into commercial production to prove if they are safe. Unfortunately, more and more scientific papers are coming out that they are not safe and cannot be made safe.
I've taken the logical and scientific choice to stop consuming these foods. During this time, although my caloric intake has not varied enough to explain the results, I lost around 130 pounds in a year: the only change I made was removing foods that are on the list.