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I have anisometropia even more extreme than yours. I wonder, have you ever tried contacts? For anisometropia, the closer the prescription is to the eyes, the better. I choose to wear glasses now, but I still have to go out of my way to find small enough frames (unfortunately out of fashion) that the lenses sit close enough to my eyes that the images converge.

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I didn't know that, but I have considered contacts for cosmetic reasons. However, they seem like an awful lot of hassle compared to glasses.

Another question: wouldn't the contacts have to be complex/progressive lenses of some kind? Clearly, I need two different prescriptions—one for computer work, one for everything else. Does staring out a bottom or top portion of a contact lens pose any difficulty beyond what one finds with progressive lenses in normal glasses?

I'm not an optometrist, and I haven't worn contacts in years. All I can tell you is that they weren't nearly as much of a hassle as people make them out to be. I just have strong, but not vision related, reasons to prefer glasses.

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