Organizations will have to decentralise in order to continue to be able to compete, grow and scale. Larger organisations, which for the most part already are distributed, will have to become even more distributed to keep up.
The big differentiator in my opinion however will be the individual's ability to work from anywhere. Not only do companies around the world spend ridiculous amounts of money on keeping everyone in the same office, there to pretend to be 'working', but nobody also seems to be willing to actually talk about the elephant in the room when it comes to environmental issues and keeping our cities from collapsing: Commuting.
Doing away with the need to commute could be a large contributing factor to fighting global warming. Yet we as a society are mostly ignoring this while at the same time seriously talking about abusing automated driving to allow people to commute even more.