I took CS221 from Andrew in 2006 (or was it 2007?) Even more has changed since then ;-) It was my second ML course, after taking Daphne Koller's punishing CS229. Right then though I knew ML will sweep the world pretty soon.
i thought Daphne Koller taught CS228. probabilistic graphical models. It was very very grueling when i took it in 05.
Daphne has a PGM course on coursera as well. From the half dozen courses I have done on coursera that was by far the most difficult one, to the point where people were talking about making t-shirts stating "I survived week 5". Personally I found it the most interesting and rewarding as well.
Oh yes my bad. I meant to say I took Andrew's CS229, and Daphne's CS228. I never took CS221.