You could basically sum it up by saying 'Startups are risky. Angel Investors are brave'.
All the risks are why Angels/VCs (including PG in his essays) are always saying they look for promising founders rather than good ideas. There are so many risks that can derail a great idea, what's important is that you can trust the people at the wheel to make the right moves.
There are a lot of technical problems in making a game, but if John Carmack is doing the coding, I'd trust him to solve them. There are a lot of gameplay problems in making a game, but if Soren Johnson is doing the design, I'd trust him to solve them.