I think RockSmith is one: https://www.youtube.com/watch?v=uaHsqGSetVo
I think there are others that might look more pedagogical.
It has some basic video lessons too.
The guitar <-> usb cable works with other programs too, though the reverse is not true (you needed to use the rocksmith adapter cable with the program).
melodics is the software to learn finger drumming (though they're adding real drums to the software).
There's a nocable patch for PC, and for Mac you can create an aggregate audio interface named "Rocksmith USB Cable" so you can use any interface you like - it's much funner with Apogee gear than the toy cable!
The biggest problem is that by learning differently, you create a real barrier between yourself and other musicians. Most guitarists learn to play in a somewhat similar manner. You learn to follow along with music and play by the tab or sheet music. The feedback you get is solely from your own ear. You learn how to stay on tempo and key from auditory cues, not visual ones. RockSmith changes all this.
RockSmith is useful to practice really difficult passages, but it becomes a major crutch at all other times and I really can't imagine someone become a well rounded guitarist while depending on it.
My process: Play slowly until you think you've nailed it. Listen to the recording, realize you didn't. Fix the parts that sound bad. Repeat until you actually nail it. Increase the metronome by 10%. Repeat until you're slightly faster than performance speed. Back off and playing at performance speed will sbe easy.