On my desktop, I have a Microsoft Natural Ergonomic 4000, which is an awesome keyboard and cheap and robust. The major compromise is that it is corded to USB, but for me it is worth it.
That said, it takes practice to develop muscle memory to use both ctl keys and both alts and key bindings that require switching ctl keys to touch type feel strange.
One day, my pinky genuinely hurt from stabbing the control key of my work-issued keyboard. I remapped the control key to caps and never looked back.
Unfortunately it only works with physical keyboards. Still use caps lock on my laptop.
Then I read somewhere that the Ctrl key used to be at the location now occupied by Caps Lock on PC keyboards. So now, on every computer I use regularly, I remap Caps Lock to be an additional Ctrl key. My pinky has thanked me for it ever since. ;-)
Also, I cannot remember having used Caps Lock ever, except by accident.
Sun put control where caps lock goes; i don't know if they originated that or if it copied someone else's existing practice.
I don't like to remap control, alt, escape, or caps-lock because I don't want to be hobbled when I use another computer that I don't control to type on. This method has worked well for me for decades.
As for Right Control - I don't think I ever pressed that key in my life...
However, even though I long ago stopped using Emacs, to this day I still swap Caps Lock with Ctrl because it's a much more natural position for the control key once you get used to it.