But I think you probably meant having and using set operations effectively in day to day tasks, as in "make 2 sets and do a set different operation" instead of "do a for loop on first hash check if it is in the second, then put results in an accumulator.
Another thing is to think about set of sets. Can that be useful sometimes? Implementing that is slightly trickier. You'd need to be able to get a hash of a set. Python has frozenset https://docs.python.org/3/library/stdtypes.html#frozenset. I've used those on occasion.
Then of course there is Erlang sofs (sets of sets) module. Stumbled on it by accident. Oh my, it comes complete with an introduction to set theory and relational algebra:
http://erlang.org/doc/man/sofs.html
It just struck me as so out of place with the rest of the standard library modules. Would like to know its history