The problem with having toxic gasses/particulates in your home, as opposed to in your garage, is that you spend
way more time in your home. Brief exposure to low levels of toxic materials is usually not a terribly big deal. Chronic exposure is much more serious, even for the same low levels.
As to what substances, the garage is used by many people to store household volatiles, which will gas off no matter how tight you screw the cap on. Add to that the exhaust fumes and it makes for a fairly unpleasant atmosphere.
Now to be fair this is all very likely to not be a problem in 99% of cases, otherwise it'd have been in the news already, but it's still a good idea to keep in mind when deciding how to store chemicals.