In principle we do not know the long-term impact in advance, but we can often make a probabilistic estimate. Choosing career as an AI researcher vs a Go player, for example.
* Note: If you want to make an impact, whichever your career inclination is, this website provides some great guides: https://80000hours.org/
I think trying to capture more of the world's resources for Google, Facebook, etc. do have a large impact in aggregation, so it's not a trivial pursuit.
DeepMind itself and many other techs to come are being funded by these companies.
Personal impact may not be extremely large since there are many other brilliant people working on the same thing but some with a leading role could make a contribution there. (For example if you work for Google, which I believe is a major force for long-term innovation.)
What I had in mind was people who spend careers on games, puzzles, or gambling. I once watched a Ke Jie interview after his loss to AlphaGo and could tell that he is brilliant and would likely be successful in other careers that require sharp thinking.
Some like Christopher Lagan needed to live a double life and is still unlikely to make any real impact on the world.
https://en.wikipedia.org/wiki/Christopher_Langan