These days, equity is for founders (if you're serious) and prospective employees who didn't get the memo about the .com bust (if you're both fools). A fixed salary at a credible professional rate is for prospective employees you respect, possibly with some clearly defined bonus structure.
YMMV, but I haven't seen any exceptions to this from either side of the table in a long time.
Of course it's an outlier, but do you really believe Facebook isn't going to make a lot of its early employees rich at some point?
But the questions don't change drastically in other types of startup either. Maybe some of the financials do, but questions about founders, business fundamentals, metrics that are focused on, how employees are assessed, etc. remain true regardless of whether it's a funded startup, bootstrapped, revenue generating, profitable or otherwise.