As human specie are we sure that we will be able to manage it?
Are we sure that the negative effect will be couter balanced by the good one? What if we get hooked to VR?
What will be the meaning of "real"?
In "The Unincorporated Man" (set 300 years in the future) the VR technology interfaced directly with the brain, so it was indistinguishable from reality. That made it extremely addictive and had nearly destroyed human civilization.
But I don't think anything less immersive, even something like OASIS from "Ready Player One" would be dangerous, or would make us to not care about the "real" world.
Precisely the same as it is now.
The issue probably will be more social (sustaining people that are hooked in through social welfare) and rise in inequality.