The UK keyboard layout still has $ above 4, but it has £ above 3. In order to get #, you have to hit ⌥3. You can also hit ⌥2 to get €. I think a couple of keys like backslash and backtick are moved around as well.
Yes. US ISO layout is superior if you need to do any programming (or even just to write some Markdown), too bad it's not used more.
On German keyboards it's even 'worse' though. Because ;, [ and ] are used for ä, ö and ü, [ and ] are Strg + ⇧ + 8 and Strg + ⇧ + 9. Same for { and }.
(Strg = Ctrl)
So any keyboard shortcut involving those and ⇧ or Ctrl is pretty much impossible.