Remote jobs certainly are more popular these days. I've been full time remote for the last 3 years and I've interviewed and resume screened a lot of candidates.

I'd be more than happy to check out your resume and give you some feedback if you wanted? You can DM me via Twitter (link in bio) or if you don't have it just let me know and we'll sort out an email.

I'd say that, since you've been out of employment for 5 years, you're definitely less than ideal candidate from employer's point of view (due to uncertainly regarding your motivation to get back to employment, team collaboration skills and attitude etc.). In my experience, remote jobs are offered to people who are almost a perfect match for the job. So, in your case, I'd start with an in-office job to disprove those risks, and then change jobs to a remote one.

Remote might be your issue.