On the software side you've got GCC, LLVM, core boot, Rust, and Google Go, all going there. There are thousands of Fedora and Debian packages already ported.
Several companies exist to support real world implementation by others - they'll help you put RISC V into whatever SoC or system you want.
This is all falling into place for an instruction set that has no production silicon yet. It's going to go somewhere. All it needs is finalized specs and some actual hardware.
Having said all that, one thing desperately missing is a free GPU. If SoCs for the public do arrive soon they will have to come from someone with graphics IP.
I don't expect Intel to be directly affected for a good while, but they will be missing out on whatever markets it takes for the next few years. I do see ARM in grave danger, but not immediately.