It makes me think that these people have never used an offline email client and don't understand what pop and imap are.
I tried mutt, i tried others.
I'm not syncing my mails anymore i just get an pop up from my webbrowser that a new email is here.
I also use different computers (home desktop, home laptop, work desktop) and prefer the same ui with the same settings on all pcs. The browser became in some way, my operating system for mails.